Lab-grown mini organs meet traffic’s invisible particles

The LIFE-NEEVE project partner IDIBE-UMH are progressing on the development of human organoids. An organoids is a miniaturised and simplified version of an organ produced in vitro in three dimensions that mimics the key functional, structural, and biological complexity of the organ.

The researchers have optimized the obtention of spheroids from different human cell lines and have also developed a full protocol to obtain skin organoids by bioprinting. The organoids are to be exposed to non-exhaust particles from brakes and tyre/road interface produced and sampled in the project revealing any toxicological effects of different road traffic non-exhaust sources.

Prof. Enrique Barrajon Catalan, who is leading the research:

We expect to finalize the particle exposure experiments later this year and hope to publish the results in early 2027